ncRNA name | miR(5,B,7) |
ncRNA Category | miRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Mus musculus |
Tissues/Cell_line | RPE and choroids |
Methods | immunostaining, Western blot, qPCR, RT-PCR |
Expression pattern | associated |
Functional description | A significant reduction in CNV was observed in a laser-induced CNV mouse model 57 days post-injection of the AAV5 particles conveying either anti-VEGFA miRNA and PEDF dual therapy or anti-VEGFA miRNA monotherapy. |
PubMed ID | 30825671 |
Year | 2019 |
Title | Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy. |
Drug-related ncRNA | NO |
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